| http://purl.uniprot.org/citations/24138883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24138883 | http://www.w3.org/2000/01/rdf-schema#comment | "Type 2 inflammatory cytokines, including interleukin-4 (IL-4), IL-5, IL-9, and IL-13, drive the characteristic features of immunity against parasitic worms and allergens. Whether IL-9 serves an essential role in the initiation of host-protective responses is controversial, and the importance of IL-9-versus IL-4-producing CD4⁺ effector T cells in type 2 immunity is incompletely defined. Herein, we generated IL-9-deficient and IL-9-fluorescent reporter mice that demonstrated an essential role for this cytokine in the early type 2 immunity against Nippostrongylus brasiliensis. Whereas T helper 9 (Th9) cells and type 2 innate lymphoid cells (ILC2s) were major sources of infection-induced IL-9 production, the adoptive transfer of Th9 cells, but not Th2 cells, caused rapid worm expulsion, marked basophilia, and increased mast cell numbers in Rag2-deficient hosts. Taken together, our data show a critical and nonredundant role for Th9 cells and IL-9 in host-protective type 2 immunity against parasitic worm infection."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.immuni.2013.07.020"xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Hao L."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Flavell R.A."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Henao-Mejia J."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Herbert D.R."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Ishigame H."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Gagliani N."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Licona-Limon I."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Licona-Limon P."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/author | "Temann A.U."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/pages | "744-757"xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/title | "Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection."xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://purl.uniprot.org/core/volume | "39"xsd:string |
| http://purl.uniprot.org/citations/24138883 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24138883 |
| http://purl.uniprot.org/citations/24138883 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24138883 |
| http://purl.uniprot.org/uniprot/#_B7ZMX3-mappedCitation-24138883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24138883 |
| http://purl.uniprot.org/uniprot/#_G3UXB0-mappedCitation-24138883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24138883 |
| http://purl.uniprot.org/uniprot/#_P07750-mappedCitation-24138883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24138883 |
| http://purl.uniprot.org/uniprot/#_Q91Y50-mappedCitation-24138883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24138883 |
| http://purl.uniprot.org/uniprot/#_Q8CD87-mappedCitation-24138883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24138883 |
| http://purl.uniprot.org/uniprot/#_P15247-mappedCitation-24138883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24138883 |