| http://purl.uniprot.org/citations/24149842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24149842 | http://www.w3.org/2000/01/rdf-schema#comment | "L7Ae is a member of a protein family that binds kink-turns (k-turns) in many functional RNA species. We have solved the X-ray crystal structure of the near-consensus sequence Kt-7 of Haloarcula marismortui bound by Archaeoglobus fulgidus L7Ae at 2.3-Å resolution. We also present a structure of Kt-7 in the absence of bound protein at 2.2-Å resolution. As a result, we can describe a general mode of recognition of k-turn structure by the L7Ae family proteins. The protein makes interactions in the widened major groove on the outer face of the k-turn. Two regions of the protein are involved. One is an α-helix that enters the major groove of the NC helix, making both nonspecific backbone interactions and specific interactions with the guanine nucleobases of the conserved G • A pairs. A hydrophobic loop makes close contact with the L1 and L2 bases, and a glutamate side chain hydrogen bonds with L1. Taken together, these interactions are highly selective for the structure of the k-turn and suggest how conformational selection of the folded k-turn occurs."xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://purl.org/dc/terms/identifier | "doi:10.1261/rna.041517.113"xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://purl.uniprot.org/core/author | "Huang L."xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://purl.uniprot.org/core/author | "Lilley D.M."xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24149842 | http://purl.uniprot.org/core/name | "RNA"xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://purl.uniprot.org/core/pages | "1703-1710"xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://purl.uniprot.org/core/title | "The molecular recognition of kink-turn structure by the L7Ae class of proteins."xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://purl.uniprot.org/core/volume | "19"xsd:string |
| http://purl.uniprot.org/citations/24149842 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24149842 |
| http://purl.uniprot.org/citations/24149842 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24149842 |
| http://purl.uniprot.org/uniprot/#_O29494-mappedCitation-24149842 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24149842 |
| http://purl.uniprot.org/uniprot/O29494 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/24149842 |