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http://purl.uniprot.org/citations/24167248http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24167248http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24167248http://www.w3.org/2000/01/rdf-schema#comment"We present the complete genomic sequence of the essential symbiont Polynucleobacter necessarius (Betaproteobacteria), which is a valuable case study for several reasons. First, it is hosted by a ciliated protist, Euplotes; bacterial symbionts of ciliates are still poorly known because of a lack of extensive molecular data. Second, the single species P. necessarius contains both symbiotic and free-living strains, allowing for a comparison between closely related organisms with different ecologies. Third, free-living P. necessarius strains are exceptional by themselves because of their small genome size, reduced metabolic flexibility, and high worldwide abundance in freshwater systems. We provide a comparative analysis of P. necessarius metabolism and explore the peculiar features of a genome reduction that occurred on an already streamlined genome. We compare this unusual system with current hypotheses for genome erosion in symbionts and free-living bacteria, propose modifications to the presently accepted model, and discuss the potential consequences of translesion DNA polymerase loss."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.org/dc/terms/identifier"doi:10.1073/pnas.1316687110"xsd:string
http://purl.uniprot.org/citations/24167248http://purl.org/dc/terms/identifier"doi:10.1073/pnas.1316687110"xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Ackerman M.S."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Ackerman M.S."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Chain P.S."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Chain P.S."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Malfatti S."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Malfatti S."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Boscaro V."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Boscaro V."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Doak T.G."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Doak T.G."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Felletti M."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Felletti M."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Lynch M."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Lynch M."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Shin M."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Shin M."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Petroni G."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Petroni G."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Vannini C."xsd:string
http://purl.uniprot.org/citations/24167248http://purl.uniprot.org/core/author"Vannini C."xsd:string