| http://purl.uniprot.org/citations/24174528 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24174528 | http://www.w3.org/2000/01/rdf-schema#comment | "Phytochromes are highly versatile photoreceptors, which occur ubiquitously in plants as well as in many light-responsive microorganisms. Here, photosynthetic cyanobacteria utilize up to three different phytochrome architectures, where only the plant-like and the single-domain cyanobacteriochromes are structurally characterized so far. Cph2 represents a third group in Synechocystis species and affects their capability of phototaxis by controlling c-di-GMP synthesis and degradation. The 2.6-Å crystal structure of its red/far-red responsive photosensory module in the Pr state reveals a tandem-GAF bidomain that lacks the figure-of-eight knot of the plant/cph1 subfamily. Its covalently attached phycocyanobilin chromophore adopts a highly tilted ZZZssa conformation with a novel set of interactions between its propionates and the GAF1 domain. The tongue-like protrusion from the GAF2 domain interacts with the GAF1-bound chromophore via its conserved PRXSF, WXE, and W(G/A)G motifs. Mutagenesis showed that the integrity of the tongue is indispensable for Pr → Pfr photoconversion and involves a swap of the motifs' tryptophans within the tongue-GAF1 interface. This "Trp switch" is supposed to be a crucial element for the photochromicity of all multidomain phytochromes."xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m113.510461"xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/author | "Mroginski M.A."xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/author | "Essen L.O."xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/author | "von Stetten D."xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/author | "Anders K."xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/author | "Daminelli-Widany G."xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/pages | "35714-35725"xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/title | "Structure of the cyanobacterial phytochrome 2 photosensor implies a tryptophan switch for phytochrome signaling."xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://purl.uniprot.org/core/volume | "288"xsd:string |
| http://purl.uniprot.org/citations/24174528 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24174528 |
| http://purl.uniprot.org/citations/24174528 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24174528 |
| http://purl.uniprot.org/uniprot/#_Q55434-mappedCitation-24174528 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24174528 |
| http://purl.uniprot.org/uniprot/Q55434 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/24174528 |