| http://purl.uniprot.org/citations/24186976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24186976 | http://www.w3.org/2000/01/rdf-schema#comment | "Both ubiquitously expressed Rad51 and meiosis-specific Dmc1 are required for crossover production during meiotic recombination. The budding yeast Rad52 and its fission yeast ortholog, Rad22, are "mediators;" i.e., they help load Rad51 onto ssDNA coated with replication protein A (RPA). Here we show that the Swi5-Sfr1 complex from fission yeast is both a mediator that loads Dmc1 onto ssDNA and a direct "activator" of DNA strand exchange by Dmc1. In stark contrast, Rad22 inhibits Dmc1 action by competing for its binding to RPA-coated ssDNA. Thus, Rad22 plays dual roles in regulating meiotic recombination: activating Rad51 and inhibiting Dmc1."xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.218693.113"xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/author | "Iwasaki H."xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/author | "Murayama Y."xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/author | "Tsutsui Y."xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/author | "Kurokawa Y."xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/pages | "2299-2304"xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/title | "Dual regulation of Dmc1-driven DNA strand exchange by Swi5-Sfr1 activation and Rad22 inhibition."xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://purl.uniprot.org/core/volume | "27"xsd:string |
| http://purl.uniprot.org/citations/24186976 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24186976 |
| http://purl.uniprot.org/citations/24186976 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24186976 |
| http://purl.uniprot.org/uniprot/O42634#attribution-029A125CD4FB5D7447AC4A2D57FEBCBC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24186976 |
| http://purl.uniprot.org/uniprot/P36592#attribution-029A125CD4FB5D7447AC4A2D57FEBCBC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24186976 |
| http://purl.uniprot.org/uniprot/Q9USV1#attribution-029A125CD4FB5D7447AC4A2D57FEBCBC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24186976 |
| http://purl.uniprot.org/uniprot/Q9UUB7#attribution-029A125CD4FB5D7447AC4A2D57FEBCBC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24186976 |
| http://purl.uniprot.org/uniprot/#_P36592-mappedCitation-24186976 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24186976 |
| http://purl.uniprot.org/uniprot/P36592 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/24186976 |