RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/24209753http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24209753http://www.w3.org/2000/01/rdf-schema#comment"Exportin5 mediates the nuclear export of double-stranded RNAs, including pre-microRNAs, adenoviral RNAs, and tRNAs. When tRNAs are aminoacylated, the Exportin5-aminoacyl (aa)-tRNA complex recruits and coexports the translation elongation factor eEF1A. Here, we show that eEF1A binds to Snail transcription factors when bound to their main target, the E-cadherin promoter, facilitating their export to the cytoplasm in association with the aa-tRNA-Exportin5 complex. Snail binds to eEF1A through the SNAG domain, a protein nuclear export signal present in several transcription factor families, and this binding is regulated by phosphorylation. Thus, we describe a nuclear role for eEF1A and provide a mechanism for protein nuclear export that attenuates the activity of SNAG-containing transcription factors."xsd:string
http://purl.uniprot.org/citations/24209753http://purl.org/dc/terms/identifier"doi:10.1016/j.celrep.2013.09.030"xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/author"Portillo F."xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/author"Vega S."xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/author"Cano A."xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/author"Nieto M.A."xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/author"Mingot J.M."xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/date"2013"xsd:gYear
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/name"Cell Rep"xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/pages"727-737"xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/title"eEF1A mediates the nuclear export of SNAG-containing proteins via the Exportin5-aminoacyl-tRNA complex."xsd:string
http://purl.uniprot.org/citations/24209753http://purl.uniprot.org/core/volume"5"xsd:string
http://purl.uniprot.org/citations/24209753http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24209753
http://purl.uniprot.org/citations/24209753http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24209753
http://purl.uniprot.org/uniprot/P68104#attribution-B631F8A0BE56775004587EAD28360E40http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/O95863#attribution-B631F8A0BE56775004587EAD28360E40http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/Q9HAV4#attribution-B631F8A0BE56775004587EAD28360E40http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/#_B3KNC6-mappedCitation-24209753http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/#_A8K5Y7-mappedCitation-24209753http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/#_B3KPQ5-mappedCitation-24209753http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/#_Q9HAV4-mappedCitation-24209753http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/#_Q9H8N6-mappedCitation-24209753http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/Q9HAV4http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24209753
http://purl.uniprot.org/uniprot/B3KPQ5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24209753