| http://purl.uniprot.org/citations/24218605 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24218605 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24218605 | http://www.w3.org/2000/01/rdf-schema#comment | "The Arabidopsis thaliana genome encodes 29 AT-hook motif containing nuclear localized (AHL) genes, which evolved into two phylogenic clades. The AHL proteins contain one or two AT-hook motif(s) and one plant and prokaryote conserved (PPC)/domain of unknown function #296 (DUF296) domain. Seedlings lacking both SOB3/AHL29 and ESC/AHL27 confer a subtle long-hypocotyl phenotype compared with the WT or either single-null mutant. In contrast, the missense allele sob3-6 confers a dramatic long-hypocotyl phenotype in the light. In this study, we examined the dominant-negative feature of sob3-6 and found that it encodes a protein with a disrupted AT-hook motif that abolishes binding to AT-rich DNA. A loss-of-function approach demonstrated different, yet redundant, contributions of additional AHL genes in suppressing hypocotyl elongation in the light. We showed that AHL proteins interact with each other and themselves via the PPC/DUF296 domain. AHLs also share interactions with other nuclear proteins, such as transcription factors, suggesting that these interactions also contribute to the functional redundancy within this gene family. The coordinated action of AHLs requires an AT-hook motif capable of binding AT-rich DNA, as well as a PPC/DUF296 domain containing a conserved Gly-Arg-Phe-Glu-Ile-Leu region. Alteration of this region abolished SOB3/AHL29's physical interaction with transcription factors and resulted in a dominant-negative allele in planta that was phenotypically similar to sob3-6. We propose a molecular model where AHLs interact with each other and themselves, as well as other nuclear proteins, to form complexes which modulate plant growth and development."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1219277110"xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1219277110"xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Zhao J."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Zhao J."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Peng H."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Peng H."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Neff M.M."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Neff M.M."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Favero D.S."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/author | "Favero D.S."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/pages | "E4688-E4697"xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/pages | "E4688-E4697"xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/title | "Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by interacting with each other via the PPC/DUF296 domain."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/title | "Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by interacting with each other via the PPC/DUF296 domain."xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/volume | "110"xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://purl.uniprot.org/core/volume | "110"xsd:string |
| http://purl.uniprot.org/citations/24218605 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24218605 |
| http://purl.uniprot.org/citations/24218605 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24218605 |