| http://purl.uniprot.org/citations/24220331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24220331 | http://www.w3.org/2000/01/rdf-schema#comment | "The effects of early postnatal maternal deprivation on the biological characteristics of the adipose tissue later in life were investigated in the present study. Sprague-Dawley rats were classified as either maternal deprivation (MD) or mother-reared control (MRC) groups. MD was achieved by separating the rat pups from their mothers for 3h each day during the 10-15 postnatal days. mRNA levels of mitochondrial uncoupling protein 1 (UCP-1), β3-adrenergic receptor (β3-AR), and prohibitin (PHB) in the brown and white adipose tissue were determined using real-time RT-PCR analysis. UCP-1, which is mediated through β3-AR, is closely involved in the energy metabolism and expenditure. PHB is highly expressed in the proliferating tissues/cells. At 10 weeks of age, the body weight of the MRC and MD rats was similar. However, the levels of the key molecules in the adipose tissue were substantially altered. There was a significant increase in the expression of PHB mRNA in the white adipose tissue, while the β3-AR mRNA expression decreased significantly, and the UCP-1 mRNA expression remained unchanged in the brown adipose tissue. Given that these molecules influence the mitochondrial metabolism, our study indicates that early postnatal maternal deprivation can influence the fate of adipose tissue proliferation, presumably leading to obesity later in life."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2013.11.005"xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Miki T."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Liu J.Q."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Ohta K."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Suzuki S."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Takeuchi Y."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Yokoyama T."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Ueki M."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Tamai M."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Kusaka T."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Jamal M."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Hosomi N."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Sumitani K."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Yakura T."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/author | "Warita K."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/pages | "68-71"xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/title | "Early postnatal maternal separation causes alterations in the expression of beta3-adrenergic receptor in rat adipose tissue suggesting long-term influence on obesity."xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://purl.uniprot.org/core/volume | "442"xsd:string |
| http://purl.uniprot.org/citations/24220331 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24220331 |
| http://purl.uniprot.org/citations/24220331 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24220331 |
| http://purl.uniprot.org/uniprot/#_A6IVX2-mappedCitation-24220331 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24220331 |