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http://purl.uniprot.org/citations/24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24227883http://www.w3.org/2000/01/rdf-schema#comment"Many stem cells, including Drosophila germline stem cells (GSCs), divide asymmetrically, producing one stem cell and one differentiating daughter. Cytokinesis is often asymmetric, in that only one daughter cell inherits the midbody ring (MR) upon completion of abscission even in apparently symmetrically dividing cells. However, whether the asymmetry in cytokinesis correlates with cell fate or has functional relevance has been poorly explored. Here we show that the MR is asymmetrically segregated during GSC divisions in a centrosome age-dependent manner: male GSCs, which inherit the mother centrosome, exclude the MR, whereas female GSCs, which we here show inherit the daughter centrosome, inherit the MR. We further show that stem cell identity correlates with the mode of MR inheritance. Together our data suggest that the MR does not inherently dictate stem cell identity, although its stereotypical inheritance is under the control of stemness and potentially provides a platform for asymmetric segregation of certain factors."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.org/dc/terms/identifier"doi:10.1091/mbc.e13-09-0541"xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/author"Chen C."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/author"Mayer M."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/author"Chiang C.Y."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/author"Yamashita Y.M."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/author"Salzmann V."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/author"Tiyaboonchai A."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/name"Mol Biol Cell"xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/pages"267-275"xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/title"Centrosome-dependent asymmetric inheritance of the midbody ring in Drosophila germline stem cell division."xsd:string
http://purl.uniprot.org/citations/24227883http://purl.uniprot.org/core/volume"25"xsd:string
http://purl.uniprot.org/citations/24227883http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24227883
http://purl.uniprot.org/citations/24227883http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24227883
http://purl.uniprot.org/uniprot/#_A0A0B4K6Z9-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_A0A0B4K863-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_A0A0B4K773-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_A0A0B4K7N9-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_A1Z9D3-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_A1Z9D4-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_O16048-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_O62528-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883
http://purl.uniprot.org/uniprot/#_P54623-mappedCitation-24227883http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24227883