http://purl.uniprot.org/citations/24242374 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24242374 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcription factor Bcl-3 functions as a proto-oncogene via regulation of cell proliferation and apoptosis. Bcl-3 is an atypical member of the IκB family and plays a central role in the immune response through interactions with the NF-κB subunits p50 and p52. To investigate the impact of Bcl-3 on B-cell maturation and regulation, we generated mice that overexpress Bcl-3 specifically in B cells. Interestingly, these mice lack marginal zone B cells and exhibit a significant reduction in the number of B-1 B cells. Further, B cells from these mice are impaired in their proliferative capacity. Our data demonstrate that the overexpression of the transcription factor Bcl-3 inhibits germinal center formation, marginal zone B-cell development, and affects the B-1 B-cell compartment."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.201343655"xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Nikolaev A."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Hahn M."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Galle P.R."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Waisman A."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Leclaire J."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Hovelmeyer N."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Worns M.A."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Reissig S."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Adams-Quack P."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/author | "Wortge S."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/name | "Eur J Immunol"xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/pages | "545-552"xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/title | "Overexpression of Bcl-3 inhibits the development of marginal zone B cells."xsd:string |
http://purl.uniprot.org/citations/24242374 | http://purl.uniprot.org/core/volume | "44"xsd:string |
http://purl.uniprot.org/citations/24242374 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24242374 |
http://purl.uniprot.org/citations/24242374 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24242374 |
http://purl.uniprot.org/uniprot/#_A0A0X1KG58-mappedCitation-24242374 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24242374 |
http://purl.uniprot.org/uniprot/#_F6YNH8-mappedCitation-24242374 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24242374 |
http://purl.uniprot.org/uniprot/#_Q3U1A5-mappedCitation-24242374 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24242374 |
http://purl.uniprot.org/uniprot/#_P25918-mappedCitation-24242374 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24242374 |
http://purl.uniprot.org/uniprot/#_Q3TQG5-mappedCitation-24242374 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24242374 |