| http://purl.uniprot.org/citations/24269686 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24269686 | http://www.w3.org/2000/01/rdf-schema#comment | "MicroRNAs (miRNAs) have recently emerged as regulators of metastasis. We provide insight into the behavior of miR-221 in colorectal cancer (CRC) metastasis by showing that miR-221 is significantly upregulated in metastatic CRC cell lines and tissues. miR-221 overexpression enhances, whereas miR-221 depletion reduces CRC cell migration and invasion in vitro and metastasis in vivo. We identify RECK as a direct target of miR-221, reveal its expression to be inversely correlated with miR-221 in CRC samples and show that its re-introduction reverses miR-221-induced CRC invasiveness. Collectively, miR-221 is an oncogenic miRNA which may regulate CRC migration and invasion through targeting RECK."xsd:string |
| http://purl.uniprot.org/citations/24269686 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2013.11.014"xsd:string |
| http://purl.uniprot.org/citations/24269686 | http://purl.uniprot.org/core/author | "Luo M."xsd:string |
| http://purl.uniprot.org/citations/24269686 | http://purl.uniprot.org/core/author | "Qin J."xsd:string |
| http://purl.uniprot.org/citations/24269686 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24269686 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/24269686 | http://purl.uniprot.org/core/pages | "99-104"xsd:string |
| http://purl.uniprot.org/citations/24269686 | http://purl.uniprot.org/core/title | "MicroRNA-221 promotes colorectal cancer cell invasion and metastasis by targeting RECK."xsd:string |
| http://purl.uniprot.org/citations/24269686 | http://purl.uniprot.org/core/volume | "588"xsd:string |
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