RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/2431040http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2431040http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2431040http://www.w3.org/2000/01/rdf-schema#comment"All HLA-B locus molecules have either the Bw4 or Bw6 epitopes. In addition, the Bw4 epitope is found on HLA-Aw23, Aw24, and A32, and Bw6 is also found on HLA-Cw3. The structural basis for these determinants and the evolution of their distribution among products of the HLA-B locus has been a long standing puzzle. To identify residues that may be involved in these determinants, we have cloned a gene for A32 and sequenced the protein encoding exons. Comparison of the predicted protein sequence with other HLA-A,B,C sequences identified residues 79 through 83 of the alpha 1 domain as having a pattern of polymorphic substitution that correlates with the presence and absence of the Bw4 and Bw6 epitopes."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Parham P."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Parham P."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Holmes N."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Holmes N."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Ennis P."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Ennis P."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Wan A.M."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/author"Wan A.M."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/date"1986"xsd:gYear
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/date"1986"xsd:gYear
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/name"J. Immunol."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/name"J. Immunol."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/pages"3671-3674"xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/pages"3671-3674"xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/title"The primary structure of HLA-A32 suggests a region involved in formation of the Bw4/Bw6 epitopes."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/title"The primary structure of HLA-A32 suggests a region involved in formation of the Bw4/Bw6 epitopes."xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/volume"137"xsd:string
http://purl.uniprot.org/citations/2431040http://purl.uniprot.org/core/volume"137"xsd:string
http://purl.uniprot.org/citations/2431040http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2431040
http://purl.uniprot.org/citations/2431040http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2431040
http://purl.uniprot.org/citations/2431040http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2431040
http://purl.uniprot.org/citations/2431040http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2431040