http://purl.uniprot.org/citations/24316228 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24316228 | http://www.w3.org/2000/01/rdf-schema#comment | "The N-terminal 1-83 residues of apolipoprotein A-I (apoA-I) have a strong propensity to form amyloid fibrils, in which the 46-59 segment was reported to aggregate to form amyloid-like fibrils. In this study, we demonstrated that a fragment peptide comprising the extreme N-terminal 1-43 residues strongly forms amyloid fibrils with a transition to β-sheet-rich structure, and that the G26R point mutation enhances the fibril formation of this segment. Our results suggest that in addition to the 46-59 segment, the extreme N-terminal region plays a crucial role in the development of amyloid fibrils by the N-terminal fragment of amyloidogenic apoA-I variants."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2013.11.031"xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Kosaka A."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Tsuji K."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Saito H."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Nagao K."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Kawashima H."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Akaji K."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Shigenaga A."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Adachi E."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Otaka A."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/author | "Mizuguchi C."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/pages | "389-394"xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/title | "The extreme N-terminal region of human apolipoprotein A-I has a strong propensity to form amyloid fibrils."xsd:string |
http://purl.uniprot.org/citations/24316228 | http://purl.uniprot.org/core/volume | "588"xsd:string |
http://purl.uniprot.org/citations/24316228 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24316228 |
http://purl.uniprot.org/citations/24316228 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24316228 |
http://purl.uniprot.org/uniprot/P02647#attribution-DC121F0B698D6A5749D883A92F7BC795 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24316228 |
http://purl.uniprot.org/uniprot/#_P02647-mappedCitation-24316228 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24316228 |
http://purl.uniprot.org/uniprot/P02647 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/24316228 |