| http://purl.uniprot.org/citations/24316890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24316890 | http://www.w3.org/2000/01/rdf-schema#comment | "Humans have ~400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms in odorant receptors alter receptor function. We identified agonists for 18 odorant receptors and found that 63% of the odorant receptors we examined had polymorphisms that altered in vitro function. On average, two individuals have functional differences at over 30% of their odorant receptor alleles. To show that these in vitro results are relevant to olfactory perception, we verified that variations in OR10G4 genotype explain over 15% of the observed variation in perceived intensity and over 10% of the observed variation in perceived valence for the high-affinity in vitro agonist guaiacol but do not explain phenotype variation for the lower-affinity agonists vanillin and ethyl vanillin."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn.3598"xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Lee S.S."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Matsunami H."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Lin A."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Zhan S."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Zhou T."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Liu W.L."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Zhuang H."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Keller A."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Adipietro K.A."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Li Y.R."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Mainland J.D."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Trimmer C."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Moberly A.H."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/author | "Snyder L.L."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/name | "Nat Neurosci"xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/pages | "114-120"xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/title | "The missense of smell: functional variability in the human odorant receptor repertoire."xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/24316890 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24316890 |
| http://purl.uniprot.org/citations/24316890 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24316890 |
| http://purl.uniprot.org/uniprot/#_P0C617-mappedCitation-24316890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24316890 |