| http://purl.uniprot.org/citations/24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24339749 | http://www.w3.org/2000/01/rdf-schema#comment | "Living organisms use biological clocks to maintain their internal temporal order and anticipate daily environmental changes. In Drosophila, circadian regulation of locomotor behavior is controlled by ∼150 neurons; among them, neurons expressing the PIGMENT DISPERSING FACTOR (PDF) set the period of locomotor behavior under free-running conditions. To date, it remains unclear how individual circadian clusters integrate their activity to assemble a distinctive behavioral output. Here we show that the BONE MORPHOGENETIC PROTEIN (BMP) signaling pathway plays a crucial role in setting the circadian period in PDF neurons in the adult brain. Acute deregulation of BMP signaling causes period lengthening through regulation of dClock transcription, providing evidence for a novel function of this pathway in the adult brain. We propose that coherence in the circadian network arises from integration in PDF neurons of both the pace of the cell-autonomous molecular clock and information derived from circadian-relevant neurons through release of BMP ligands."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pbio.1001733"xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/author | "Beckwith E.J."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/author | "Ceriani M.F."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/author | "Nadra A.D."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/author | "Berni J."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/author | "Rezaval C."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/author | "Gorostiza E.A."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/author | "Perez-Santangelo A."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/date | "2013"xsd:gYear |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/name | "PLoS Biol"xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/pages | "e1001733"xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/title | "Circadian period integrates network information through activation of the BMP signaling pathway."xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/24339749 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24339749 |
| http://purl.uniprot.org/citations/24339749 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24339749 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KFC0-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |
| http://purl.uniprot.org/uniprot/#_A0A1W5PW00-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K7J3-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |
| http://purl.uniprot.org/uniprot/#_A0A0B4LGA7-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |
| http://purl.uniprot.org/uniprot/#_A0A9F2GM11-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |
| http://purl.uniprot.org/uniprot/#_A1Z8F4-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |
| http://purl.uniprot.org/uniprot/#_A0A6H2EEY2-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |
| http://purl.uniprot.org/uniprot/#_P49021-mappedCitation-24339749 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24339749 |