| http://purl.uniprot.org/citations/24382668 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24382668 | http://www.w3.org/2000/01/rdf-schema#comment | "Our previous microarray data showed that microRNA-224 (miR-224) was downregulated in human prostate cancer (PCa) tissues compared with adjacent benign tissues. However, the underlying mechanisms by which miR-224 is involved in PCa remain unclear. In this study, we identified TRIB1 as a target gene of miR-224. Forced expression of miR-224 suppressed PCa cell proliferation, invasion and migration, and promoted cell apoptosis by downregulating TRIB1. Moreover, the expression level of miR-224 in PCa tissues was negatively correlated with that of TRIB1. miR-224 downregulation was frequently found in PCa tissues with metastasis, higher PSA level and clinical stage, whereas TRIB1 upregulation was significantly associated with metastasis. Both miR-224 downregulation and TRIB1 upregulation were significantly associated with poor biochemical recurrence-free survival of patients with PCa. In conclusion, these findings reveal that the aberrant expression of miR-224 and TRIB1 may promote PCa progression and have potentials to serve as novel biomarkers for PCa prognosis."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.org/dc/terms/identifier | "doi:10.1002/ijc.28707"xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Chen J.H."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Wang F."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Fu X."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Huang Y.Q."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Liang Y.X."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Cai C."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Zhang Y.Q."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Wu C.L."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Lin Z.Y."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Han Z.D."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Dai Q.S."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "He H.C."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Zhong W.D."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Jiang F.N."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/author | "Ling X.H."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/name | "Int J Cancer"xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/pages | "541-550"xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/title | "MicroRNA-224 inhibits progression of human prostate cancer by downregulating TRIB1."xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://purl.uniprot.org/core/volume | "135"xsd:string |
| http://purl.uniprot.org/citations/24382668 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24382668 |
| http://purl.uniprot.org/citations/24382668 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24382668 |