| http://purl.uniprot.org/citations/24407287 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24407287 | http://www.w3.org/2000/01/rdf-schema#comment | "The apoptosis-associated speck-like protein containing a caspase-activating recruitment domain (ASC) is an essential component of several inflammasomes, multiprotein complexes that regulate caspase-1 activation and inflammation. We report here an interaction between promyelocytic leukemia protein (PML) and ASC. We observed enhanced formation of ASC dimers in PML-deficient macrophages. These macrophages also display enhanced levels of ASC in the cytosol. Furthermore, IL-1β production was markedly enhanced in these macrophages in response to both NLRP3 and AIM2 inflammasome activation and following bone marrow-derived macrophage infection with herpes simplex virus-1 (HSV-1) and Salmonella typhimurium. Collectively, our data indicate that PML limits ASC function, retaining ASC in the nucleus."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m113.539692"xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Becker C.E."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Pandolfi P.P."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Bourke N.M."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Mansell A."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Connolly D.J."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "O'Neill L.A.J."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Quinn S.R."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Dowling J.K."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/author | "Corr S.C."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/pages | "6429-6437"xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/title | "Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation."xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://purl.uniprot.org/core/volume | "289"xsd:string |
| http://purl.uniprot.org/citations/24407287 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24407287 |
| http://purl.uniprot.org/citations/24407287 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24407287 |
| http://purl.uniprot.org/uniprot/Q9EPB4#attribution-0AD49D61EE324CA7FB4CF437DF2BDF70 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24407287 |
| http://purl.uniprot.org/uniprot/Q9EPB4#attribution-2B56B8B6BBE3C34A90D252B27AB8676B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24407287 |
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| http://purl.uniprot.org/uniprot/Q60953#attribution-0AD49D61EE324CA7FB4CF437DF2BDF70 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24407287 |
| http://purl.uniprot.org/uniprot/#_A0A068EW80-mappedCitation-24407287 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24407287 |
| http://purl.uniprot.org/uniprot/#_D3YXR5-mappedCitation-24407287 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24407287 |