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http://purl.uniprot.org/citations/24418574 | http://www.w3.org/2000/01/rdf-schema#comment | "Pancreatic cancer is a devastating disease with an overall 5-year survival rate less than 5%. Multiple signaling pathways are implicated in the pathogenesis of pancreatic cancer, such as Wnt/β-catenin, Notch, Hedgehog, hypoxia-inducible factor, signal transducer and activator of transcription, specificity proteins/Krüppel-like factors, and Forkhead box (FOX). Recently, increasing evidence has demonstrated that the transcription factor FOXM1 plays important roles in the initiation, progression, and metastasis of a variety of human tumors, including pancreatic cancer. In this review, we focus on the current understanding of the molecular pathogenesis of pancreatic cancer with a special focus on the function and regulation of FOXM1 and rationale for FOXM1 as a novel molecular target for pancreatic cancer prevention and treatment."xsd:string |
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http://purl.uniprot.org/citations/24418574 | http://purl.uniprot.org/core/author | "Du J."xsd:string |
http://purl.uniprot.org/citations/24418574 | http://purl.uniprot.org/core/author | "Huang C."xsd:string |
http://purl.uniprot.org/citations/24418574 | http://purl.uniprot.org/core/author | "Xie K."xsd:string |
http://purl.uniprot.org/citations/24418574 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/24418574 | http://purl.uniprot.org/core/name | "Biochim Biophys Acta"xsd:string |
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http://purl.uniprot.org/citations/24418574 | http://purl.uniprot.org/core/title | "FOXM1 and its oncogenic signaling in pancreatic cancer pathogenesis."xsd:string |
http://purl.uniprot.org/citations/24418574 | http://purl.uniprot.org/core/volume | "1845"xsd:string |
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