| http://purl.uniprot.org/citations/24440351 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24440351 | http://www.w3.org/2000/01/rdf-schema#comment | "We hypothesized that C-reactive protein (CRP) may affect the cell cycle and induce apoptotic changes of monocytes. CRP (∼25 μg/ml) significantly increased expressions of B-cell translocation gene 2 (BTG2) mRNA and protein in human monocytes through pathways involving CD32/NADPH oxidase 2/p53, which eventually induced G2/M phase arrest and apoptotic cell death. Such pro-apoptotic effect of CRP was not found in thioglycollate-elicited intraperitoneal monocytes/macrophages harvested from BTG2-knockout male C57BL/6 mice (n=5). Within atheromatous plaques obtained from CRP-transgenic male LDLR(-/-) C57BL/6 mice (n=5) and human coronary arteries, BTG2 co-localized with CRP, p53 and monocytes/macrophages. Therefore the pro-apoptotic pathway of CRP-CD32-Nox2-p53-BTG2 may contribute to the retardation of the atherogenic process."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2014.01.008"xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/author | "Kim Y."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/author | "Lim S."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/author | "Han K.H."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/author | "Lim I.K."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/author | "Ryu M.S."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/author | "Ryu J."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/author | "Han K.O."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/pages | "625-631"xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/title | "C-reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B-cell translocation gene 2 expression."xsd:string |
| http://purl.uniprot.org/citations/24440351 | http://purl.uniprot.org/core/volume | "588"xsd:string |
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