| http://purl.uniprot.org/citations/24497532 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24497532 | http://www.w3.org/2000/01/rdf-schema#comment | "The pathogenesis of primary mediastinal large B-cell lymphoma (PMBCL) is incompletely understood. Recently, specific genotypic and phenotypic features have been linked to tumor cell immune escape mechanisms in PMBCL. We studied 571 B-cell lymphomas with a focus on PMBCL. Using fluorescence in situ hybridization here, we report that the programmed death ligand (PDL) locus (9p24.1) is frequently and specifically rearranged in PMBCL (20%) as compared with diffuse large B-cell lymphoma, follicular lymphoma, and Hodgkin lymphoma. Rearrangement was significantly correlated with overexpression of PDL transcripts. Utilizing high-throughput sequencing techniques, we characterized novel translocations and chimeric fusion transcripts involving PDLs at base-pair resolution. Our data suggest that recurrent genomic rearrangement events underlie an immune privilege phenotype in a subset of B-cell lymphomas."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.org/dc/terms/identifier | "doi:10.1182/blood-2013-10-535443"xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Shah S.P."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Tan K.L."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Gascoyne R.D."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Scott D.W."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Steidl C."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Woolcock B.W."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Ben-Neriah S."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Savage K.J."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Lim R.S."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Gunawardana J."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Mottok A."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Chan F.C."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Telenius A."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Slack G.W."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Kridel R."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "McPherson A.W."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/author | "Twa D.D."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/name | "Blood"xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/pages | "2062-2065"xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/title | "Genomic rearrangements involving programmed death ligands are recurrent in primary mediastinal large B-cell lymphoma."xsd:string |
| http://purl.uniprot.org/citations/24497532 | http://purl.uniprot.org/core/volume | "123"xsd:string |