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http://purl.uniprot.org/citations/24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24531141http://www.w3.org/2000/01/rdf-schema#comment"PA28γ (also called REGγ, 11Sγ or PSME3) negatively regulates p53 activity by promoting its nuclear export and/or degradation. Here, using the RNA ligase-mediated rapid amplification of cDNA ends (RLM-RACE) method, we identified the transcription start site of the PA28γ gene. Assessment with the luciferase assay demonstrated that the sequence -193 to +16 is the basal promoter. Three p53 binding sites were found within the PA28γ promoter utilizing a bioinformatics approach and were confirmed by chromatin immunoprecipitation and biotinylated DNA affinity precipitation experiments. The p53 protein promotes PA28γ transcription, and p53-stimulated transcription of PA28γ can be inhibited by PA28γ itself. Our results suggest that PA28γ and p53 form a negative feedback loop, which maintains the balance of p53 and PA28γ in cells."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.org/dc/terms/identifier"doi:10.3390/ijms15022573"xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/author"Zhou J."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/author"Yi X."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/author"Zhou J.L."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/author"Xu Z.X."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/author"Wan Z.X."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/author"Yuan D.M."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/author"Zhuo Y.M."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/name"Int J Mol Sci"xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/pages"2573-2584"xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/title"The proteasome activator PA28gamma, a negative regulator of p53, is transcriptionally up-regulated by p53."xsd:string
http://purl.uniprot.org/citations/24531141http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/24531141http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24531141
http://purl.uniprot.org/citations/24531141http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24531141
http://purl.uniprot.org/uniprot/#_B7Z8D3-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141
http://purl.uniprot.org/uniprot/#_B3KQ25-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141
http://purl.uniprot.org/uniprot/#_J7FRP4-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141
http://purl.uniprot.org/uniprot/#_K9J957-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141
http://purl.uniprot.org/uniprot/#_P61289-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141
http://purl.uniprot.org/uniprot/#_Q6FHK7-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141
http://purl.uniprot.org/uniprot/#_Q6MZZ1-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141
http://purl.uniprot.org/uniprot/#_V9HWJ8-mappedCitation-24531141http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24531141