| http://purl.uniprot.org/citations/24558260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24558260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24558260 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24558260 | http://www.w3.org/2000/01/rdf-schema#comment | "Pseudo-homothallism is a reproductive strategy elected by some fungi producing heterokaryotic sexual spores containing genetically different but sexually compatible nuclei. This lifestyle appears as a compromise between true homothallism (self-fertility with predominant inbreeding) and complete heterothallism (with exclusive outcrossing). However, pseudohomothallic species face the problem of maintaining heterokaryotic mycelia to fully benefit from this lifestyle, as homokaryons are self-sterile. Here, we report on the structure of chromosome 1 in mat+ and mat-isolates of strain S of the pseudohomothallic fungus Podospora anserina. Chromosome 1 contains either one of the mat+ and mat-mating types of P. anserina, which is mostly found in nature as a mat+/mat-heterokaryotic mycelium harboring sexually compatible nuclei. We identified a "mat" region ∼0.8 Mb long, devoid of meiotic recombination and containing the mating-type idiomorphs, which is a candidate to be involved in the maintenance of the heterokaryotic state, since the S mat+ and S mat-strains have different physiology that may enable hybrid-vigor-like phenomena in the heterokaryons. The mat region contains 229 coding sequences. A total of 687 polymorphisms were detected between the S mat+ and S mat-chromosomes. Importantly, the mat region is colinear between both chromosomes, which calls for an original mechanism of recombination inhibition. Microarray analyses revealed that 10% of the P. anserina genes have different transcriptional profiles in S mat+ and S mat-, in line with their different phenotypes. Finally, we show that the heterokaryotic state is faithfully maintained during mycelium growth of P. anserina, yet mat+/mat+ and mat-/mat-heterokaryons are as stable as mat+/mat-ones, evidencing a maintenance of heterokaryosis that does not rely on fitness-enhancing complementation between the S mat+ and S mat- strains."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.113.159988"xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.113.159988"xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.org/dc/terms/identifier | "doi:10.1534/genetics.113.159988"xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Couloux A."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Couloux A."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Couloux A."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Wincker P."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Wincker P."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Wincker P."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Benkhali J.A."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Benkhali J.A."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Benkhali J.A."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Bidard F."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Bidard F."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Bidard F."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Coppin E."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Coppin E."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Coppin E."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Debuchy R."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Debuchy R."xsd:string |
| http://purl.uniprot.org/citations/24558260 | http://purl.uniprot.org/core/author | "Debuchy R."xsd:string |