| http://purl.uniprot.org/citations/24598915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24598915 | http://www.w3.org/2000/01/rdf-schema#comment | "The antibody IgE plays a central role in allergic disease, functioning principally through two cell-surface receptors: FcℇRI and CD23. FcℇRI on mast cells and basophils mediates the immediate hypersensitivity response, whilst the interaction of IgE with CD23 on B cells regulates IgE production. Crystal structures of the lectin-like `head' domain of CD23 alone and bound to a subfragment of IgE consisting of the dimer of Cℇ3 and Cℇ4 domains (Fcℇ3-4) have recently been determined, revealing flexibility in the IgE-binding site of CD23. Here, a new crystal form of the CD23-Fcℇ3-4 complex with different molecular-packing constraints is reported, which together with the earlier results demonstrates that conformational variability at the interface extends additionally to the IgE Fc and the quaternary structure of its domains."xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.org/dc/terms/identifier | "doi:10.1107/s2053230x14003355"xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/author | "Sutton B.J."xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/author | "Dhaliwal B."xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/author | "Yuan D."xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/author | "Beavil A.J."xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/author | "Pang M.O."xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/name | "Acta Crystallogr F Struct Biol Commun"xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/pages | "305-309"xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/title | "A range of Cℇ3-Cℇ4 interdomain angles in IgE Fc accommodate binding to its receptor CD23."xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://purl.uniprot.org/core/volume | "70"xsd:string |
| http://purl.uniprot.org/citations/24598915 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24598915 |
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| http://purl.uniprot.org/uniprot/#_P01854-mappedCitation-24598915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24598915 |
| http://purl.uniprot.org/uniprot/#_K3W4U1-mappedCitation-24598915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24598915 |
| http://purl.uniprot.org/uniprot/#_Q30218-mappedCitation-24598915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24598915 |
| http://purl.uniprot.org/uniprot/#_Q30219-mappedCitation-24598915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24598915 |
| http://purl.uniprot.org/uniprot/#_P06734-mappedCitation-24598915 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24598915 |
| http://purl.uniprot.org/uniprot/P01854 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/24598915 |
| http://purl.uniprot.org/uniprot/Q30219 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/24598915 |
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