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http://purl.uniprot.org/citations/24606480http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24606480http://www.w3.org/2000/01/rdf-schema#comment"Squamous cell/adenosquamous carcinoma (SC/ASC) of the gallbladder are rare tumors and there are few clinical reports in the literature. Herein we report our clinical experience with 46 patients with SC/ASC and 80 with adenocarcinoma (AC). Expression of EphB1 and Ephrin-B in each tumor was determined using immunohistochemical methods for determination of correlations with prognosis. There was no difference in EphB1 and Ephrin-B expression between SC/ASC and AC tumors (P>0.05), but greater expression in those less than 3 cm in diameter, stage I or II (TNM stage), with no lymph node metastases, with no local invasion and treated with radical resection was apparent. Expression of EphB1 (P<0.05) and Ephrin-B (P<0.01) was higher in well differentiated than in poorly differentiated AC tumors. Kaplan-Meier survival analysis indicated that degree of differentiation, tumor diameter, lymph node metastases, local invasion, surgical approach and expression rate of EphB1 and Ephrin-B were closely related to the survival of SC/ASC (P<0.05) and AC patients (P<0.01). Patients with tumors that positive expressed EphB1 and Ephrin-B, whether it is SC/ASC (P SC/ASC =0.000) or AC (P AC =0.000 or P AC =0.002) had longer survival than those negative expression. Cox multivariate analysis indicated a negative correlation between expression of EphB1 or Ephrin-B and overall survival. Hence, EphB1 and Ephrin-B could be regarded as independent good prognostic factorsand important biological markers for SC/ASC and AC of gallbladder."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.org/dc/terms/identifier"doi:10.7314/apjcp.2014.15.3.1441"xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Chen S.L."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Li J.H."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Yuan Y."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Zou Q."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Yang Z.L."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Li D.Q."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Liu Z.R."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Miao X.Y."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Liang L.F."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/author"Zeng G.X."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/name"Asian Pac J Cancer Prev"xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/pages"1441-1446"xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/title"EphB1 and Ephrin-B, new potential biomarkers for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder."xsd:string
http://purl.uniprot.org/citations/24606480http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/24606480http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24606480
http://purl.uniprot.org/citations/24606480http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24606480
http://purl.uniprot.org/uniprot/#_P54762-mappedCitation-24606480http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24606480
http://purl.uniprot.org/uniprot/P54762http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24606480