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http://purl.uniprot.org/citations/24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24607481http://www.w3.org/2000/01/rdf-schema#comment"In this study, we demonstrate that the 7SK small nuclear ribonucleoprotein (snRNP) complex is recruited to the HIV-1 promoter via newly-synthesized HIV-1 nascent transcripts (short transcripts) in an hnRNP A1-dependent manner and negatively regulates viral transcript elongation. Our deep-sequence analysis showed these short transcripts were mainly arrested at approximately +50 to +70 nucleotides from the transcriptional start site in the U1 cells, an HIV-1 latent model. TNF-α treatment promptly disrupted the 7SK snRNP complex on the nascent transcripts and viral elongated transcripts were increased. This report provides insight into how 7SK snRNP complex is recruited to HIV-1 promoter in the absence of Tat."xsd:string
http://purl.uniprot.org/citations/24607481http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2014.01.067"xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/author"Suzuki Y."xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/author"Iba H."xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/author"Mizutani T."xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/author"Ishizaka A."xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/pages"1630-1636"xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/title"7SK small nuclear ribonucleoprotein complex is recruited to the HIV-1 promoter via short viral transcripts."xsd:string
http://purl.uniprot.org/citations/24607481http://purl.uniprot.org/core/volume"588"xsd:string
http://purl.uniprot.org/citations/24607481http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24607481
http://purl.uniprot.org/citations/24607481http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24607481
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http://purl.uniprot.org/uniprot/#_Q05CL8-mappedCitation-24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24607481
http://purl.uniprot.org/uniprot/#_P49312-mappedCitation-24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24607481
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http://purl.uniprot.org/uniprot/#_Q3U7F3-mappedCitation-24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24607481
http://purl.uniprot.org/uniprot/#_Q3UK83-mappedCitation-24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24607481
http://purl.uniprot.org/uniprot/#_Q5EBP8-mappedCitation-24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24607481
http://purl.uniprot.org/uniprot/#_Q4G0J3-mappedCitation-24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24607481
http://purl.uniprot.org/uniprot/#_Q96IZ8-mappedCitation-24607481http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24607481