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http://purl.uniprot.org/citations/2462511http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2462511http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2462511http://www.w3.org/2000/01/rdf-schema#comment"Pardaxin, an amphipathic polypeptide secreted by the Red Sea flatfish Pardachirus marmoratus whose sequence is NH2-G-F-F-A-L-I-P-K-I-I-S-S-P-L-F-K-T-L-L-S-A-V-G-S-A-L-S-S-S-G-G-Q-E, was synthesized by the solid-phase method. The structure was verified by sequencing. The synthetic polypeptide changed the resistance of lipid bilayers by forming pores. At 10(-7)-10(-8) M, the synthetic pardaxin increased the frequency of the spontaneous release of quanta of acetylcholine at the neuromuscular junction by up to 100-fold, resembling the native product. Synthetic pardaxin seems to be a suitable tool for investigating the molecular structures underlying channel selectivity."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(88)81007-x"xsd:string
http://purl.uniprot.org/citations/2462511http://purl.org/dc/terms/identifier"doi:10.1016/0014-5793(88)81007-x"xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Shai Y."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Shai Y."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Shih Y.-L."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Shih Y.-L."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Edwards C."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Edwards C."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Fox J."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Fox J."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Lazarovici P."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Lazarovici P."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Caratsch C."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/author"Caratsch C."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/date"1988"xsd:gYear
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/pages"161-166"xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/pages"161-166"xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/title"Sequencing and synthesis of pardaxin, a polypeptide from the Red sea moses sole with ionophore activity."xsd:string
http://purl.uniprot.org/citations/2462511http://purl.uniprot.org/core/title"Sequencing and synthesis of pardaxin, a polypeptide from the Red sea moses sole with ionophore activity."xsd:string