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http://purl.uniprot.org/citations/24650662http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24650662http://www.w3.org/2000/01/rdf-schema#comment"RNA binding proteins control gene expression by the attenuation/antitermination mechanism. HutP is an RNA binding antitermination protein. It regulates the expression of hut operon when it binds with RNA by modulating the secondary structure of single-stranded hut mRNA. HutP necessitates the presence of l-histidine and divalent metal ion to bind with RNA. Herein, we report the crystal structures of ternary complex (HutP-l-histidine-Mg(2+)) and EDTA (0.5 M) treated ternary complex (HutP-l-histidine-Mg(2+)), solved at 1.9 Å and 2.5 Å resolutions, respectively, from Geobacillus thermodenitrificans. The addition of 0.5 M EDTA does not affect the overall metal-ion mediated ternary complex structure and however, the metal ions at the non-specific binding sites are chelated, as evidenced from the results of structural features."xsd:string
http://purl.uniprot.org/citations/24650662http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2014.03.036"xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/author"Kumarevel T."xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/author"Ponnuswamy M.N."xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/author"Sivaraman P."xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/author"Thiruselvam V."xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/pages"945-951"xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/title"Crystal structure of the single-stranded RNA binding protein HutP from Geobacillus thermodenitrificans."xsd:string
http://purl.uniprot.org/citations/24650662http://purl.uniprot.org/core/volume"446"xsd:string
http://purl.uniprot.org/citations/24650662http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24650662
http://purl.uniprot.org/citations/24650662http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24650662
http://purl.uniprot.org/uniprot/#_A4IK89-mappedCitation-24650662http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24650662
http://purl.uniprot.org/uniprot/A4IK89http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24650662