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http://purl.uniprot.org/citations/24687979http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24687979http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24687979http://www.w3.org/2000/01/rdf-schema#comment"The Arabidopsis stoma is a specialized epidermal valve made up of a pair of guard cells around a pore whose aperture controls gas exchange between the shoot and atmosphere. Guard cells (GCs) are produced by a symmetric division of guard mother cells (GMCs). The R2R3-MYB transcription factor FOUR LIPS (FLP) and its paralogue MYB88 restrict the division of a GMC to one. Previously, the upstream regions of several core cell cycle genes were identified as the direct targets of FLP/MYB88, including the B-type cyclin-dependent kinase CDKB1;1 and A2-type cyclin CYCA2;3. Here we show that CDKA;1 is also an immediate direct target of FLP/MYB88 through the binding to cis-regulatory elements in the CDKA;1 promoter region. CDKA;1 activity is required not only for normal GMC divisions but also for the excessive cell overproliferation in flp myb88 mutant GMCs. The impaired defects of GMC division in cdkb1;1 1;2 mutants could be partially rescued by a stage-specific expression of CDKA;1. Although targeted overexpression of CDKA;1 does not affect stomatal development, ectopic expression of the D3-type cyclin CYCD3;2 induces GC subdivision, resulting in a stoma with 3-4 GCs instead of the normal two. Co-overexpression of CDKA;1 with CYCD3;2, but not with CYCA2;3, confers a synergistic effect with respect to GC subdivision. Thus, in addition to a role in stomatal formative asymmetric divisions at early developmental stages, CDKA;1 is needed in triggering GMC symmetric divisions at the late stage of stomatal development. However, timely down-regulation of CDKA;1-CYCD3 activity is required for restriction of GC proliferation."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.org/dc/terms/identifier"doi:10.1093/jxb/eru139"xsd:string
http://purl.uniprot.org/citations/24687979http://purl.org/dc/terms/identifier"doi:10.1093/jxb/eru139"xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Le J."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Le J."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Qu X."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Qu X."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Yang K."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Yang K."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Wang H."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Wang H."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Xue S."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Xue S."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Zou J."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/author"Zou J."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/name"J. Exp. Bot."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/name"J. Exp. Bot."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/pages"2449-2461"xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/pages"2449-2461"xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/title"Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis."xsd:string
http://purl.uniprot.org/citations/24687979http://purl.uniprot.org/core/title"Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis."xsd:string