| http://purl.uniprot.org/citations/24708417 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24708417 | http://www.w3.org/2000/01/rdf-schema#comment | "The binding of NKG2D to its ligands strengthens the cross-talk between natural killer (NK) cells and dendritic cells, particularly at early stages, before the initiation of the adaptive immune response. We found that retinoic acid early transcript-1ε (RAE-1ε), one of the ligands of NKG2D, was persistently expressed on antigen-presenting cells in a transgenic mouse model (pCD86-RAE-1ε). By contrast, NKG2D expression on NK cells, NKG2D-dependent cytotoxicity and tumour rejection, and dextran sodium sulphate-induced colitis were all down-regulated in this mouse model. The down-regulation of NKG2D on NK cells was reversed by stimulation with poly (I:C). The ectopic expression of RAE-1ε on dendritic cells maintained NKG2D expression levels and stimulated the activity of NK cells ex vivo, but the higher frequency of CD4(+) NKG2D(+) T cells in transgenic mice led to the down-regulation of NKG2D on NK cells in vivo. Hence, high levels of RAE-1ε expression on antigen-presenting cells would be expected to induce the down-regulation of NK cell activation by a regulatory T-cell subset."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.org/dc/terms/identifier | "doi:10.1111/imm.12203"xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Ding Y."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Gong W."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Liu W."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Lin Z."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Jia X."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Ji M."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Wang C."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Xiao W."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Xia H."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/author | "Qian L."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/name | "Immunology"xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/pages | "401-415"xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/title | "CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1epsilon transgenic mice."xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://purl.uniprot.org/core/volume | "141"xsd:string |
| http://purl.uniprot.org/citations/24708417 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24708417 |
| http://purl.uniprot.org/citations/24708417 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24708417 |
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| http://purl.uniprot.org/uniprot/#_D7F2B4-mappedCitation-24708417 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24708417 |
| http://purl.uniprot.org/uniprot/#_D7F2B6-mappedCitation-24708417 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24708417 |
| http://purl.uniprot.org/uniprot/#_D7F2B7-mappedCitation-24708417 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24708417 |
| http://purl.uniprot.org/uniprot/#_P42082-mappedCitation-24708417 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24708417 |