| http://purl.uniprot.org/citations/24728959 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24728959 | http://www.w3.org/2000/01/rdf-schema#comment | "The HMGA1 and HMGA2 genes code for proteins belonging to the High Mobility Group A family. Several genes are negatively or positively regulated by both these proteins, but a number of genes are specifically regulated by only one of them. Indeed, knock-out of the Hmga1 and Hmga2 genes leads to different phenotypes: cardiac hypertrophy and type 2 diabetes in the former case, and a large reduction in body size and amount of fat tissue in the latter case. Therefore, to better elucidate the functions of the Hmga genes, we crossed Hmga1-null mice with mice null for Hmga2. The Hmga1(-/-)/Hmga2(-/-) mice showed reduced vitality and a very small size (75% smaller than the wild-type mice); they were even smaller than pygmy Hmga2-null mice. The drastic reduction in E2F1 activity, and consequently in the expression of the E2F-dependent genes involved in cell cycle regulation, likely accounts for some phenotypic features of the Hmga1(-/-)/Hmga2(-/-) mice."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.org/dc/terms/identifier | "doi:10.1242/bio.20146759"xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Fedele M."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Fusco A."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Federico A."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Esposito F."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Arra C."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Pierantoni G.M."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Barbieri A."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Palma G."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Palmieri D."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "De Martino I."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/author | "Forzati F."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/name | "Biol Open"xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/pages | "372-378"xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/title | "Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotype."xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/24728959 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24728959 |
| http://purl.uniprot.org/citations/24728959 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24728959 |
| http://purl.uniprot.org/uniprot/P52927#attribution-89FC525955C0EDCA18F8D0311E481F33 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24728959 |
| http://purl.uniprot.org/uniprot/P17095#attribution-0285DBFF9F3A8D925EF4CA6419428460 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24728959 |
| http://purl.uniprot.org/uniprot/P17095#attribution-89FC525955C0EDCA18F8D0311E481F33 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/24728959 |
| http://purl.uniprot.org/uniprot/#_P52927-mappedCitation-24728959 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24728959 |