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| http://purl.uniprot.org/citations/24740533 | http://www.w3.org/2000/01/rdf-schema#comment | "The leukemia-associated ETV6-RUNX1-translocation frequently emerges prenatally. Reverse-transcriptase PCR screening may indicate presence of ETV6-RUNX1 transcripts in random cord blood samples. Subsequent cell enrichment validation finds significantly lower levels than validation applying fluorescence in situ hybridization (FISH) (<10(-5) vs. 10(-3) to 10(-4)). Using three FISH probe sets, we screened 179,000 cells from ETV6-RUNX1-positive dilution series, healthy adults and random cord blood samples. The t(12;21) single fusion extra signal translocation probe and the ETV6 break apart probe gave false positive results mimicking ETV6-RUNX1-positive cell levels of 10(-3). This questions the paradigm that 1% of newborns have ETV6-RUNX1-positive cells at levels of 10(-3) to 10(-4)."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.org/dc/terms/identifier | "doi:10.1002/pbc.25050"xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/author | "Olsen M."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/author | "Andersen M.K."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/author | "Hjalgrim H."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/author | "Schmiegelow K."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/author | "Lausten-Thomsen U."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/author | "Kusk M.S."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/name | "Pediatr Blood Cancer"xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/pages | "1704-1706"xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/title | "False positivity of ETV6/RUNX1 detected by FISH in healthy newborns and adults."xsd:string |
| http://purl.uniprot.org/citations/24740533 | http://purl.uniprot.org/core/volume | "61"xsd:string |
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