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http://purl.uniprot.org/citations/24785584http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24785584http://www.w3.org/2000/01/rdf-schema#comment"

Objective

Heart-type fatty acid binding protein (H-FABP) is a tissue-specific protein which is rapidly released into the circulation when cardiomyocyte injury occurs. The aim of the study is to investigate the prognostic relevance of H-FABP for out-of-hospital cardiac arrest (OHCA) patients in the early post-cardiac arrest period.

Design and methods

This is a prospective cohort study enrolling non-traumatic resuscitated OHCA patients.

Results

A total of 106 patients were enrolled. The H-FABP level at 24h was correlated to the duration from collapse to return of spontaneous circulation (p<0.001, R(2)=0.549). The outcomes of survival to discharge were worse in the patient group with the higher tertile of plasma H-FABP level at 24h after the event (p=0.011). Multivariate analysis demonstrated that the significant predictors for in-hospital mortality were APACHE II score (p=0.010), gender (p=0.025) and the tertiles of H-FABP at 24h with hazard ratios for the lowest, middle, and highest tertiles being 1.0, 1.157 (95% confidence interval 0.435-3.075, p=0.770), and 2.840 (95% confidence interval 1.137-7.092, p=0.025), respectively.

Conclusion

The plasma level of H-FABP at 24h after the event may be an early and independent factor associated with survival to discharge in OHCA patients."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.org/dc/terms/identifier"doi:10.1016/j.cca.2014.04.014"xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Chang W.T."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Hsu C.Y."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Huang C.H."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Chen S.C."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Chen W.J."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Tsai M.S."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Ma M.H."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Wang T.D."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/author"Chien K.L."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/name"Clin Chim Acta"xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/pages"7-13"xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/title"Prognostic relevance of plasma heart-type fatty acid binding protein after out-of-hospital cardiac arrest."xsd:string
http://purl.uniprot.org/citations/24785584http://purl.uniprot.org/core/volume"435"xsd:string
http://purl.uniprot.org/citations/24785584http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24785584
http://purl.uniprot.org/citations/24785584http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24785584
http://purl.uniprot.org/uniprot/#_A0A384MDY5-mappedCitation-24785584http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24785584
http://purl.uniprot.org/uniprot/#_P05413-mappedCitation-24785584http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24785584
http://purl.uniprot.org/uniprot/#_Q6IBD7-mappedCitation-24785584http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24785584
http://purl.uniprot.org/uniprot/A0A384MDY5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24785584
http://purl.uniprot.org/uniprot/P05413http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24785584
http://purl.uniprot.org/uniprot/Q6IBD7http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/24785584
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