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| Subject | Predicate | Object |
|---|---|---|
| http://purl.uniprot.org/citations/24815426 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24815426 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24815426 | http://www.w3.org/2000/01/rdf-schema#comment | "The African origin of hominins suggests that Taenia spp. in African carnivores are evolutionarily related to the human-infecting tapeworms Taenia solium, Taenia saginata and Taenia asiatica. Nevertheless, the hypothesis has not been verified through molecular phylogenetics of Taenia. This study aimed to perform phylogenetic comparisons between Taenia spp. from African hyenas and the congeneric human parasites. During 2010-2013, 233 adult specimens of Taenia spp. were collected from 11 spotted hyenas in Ethiopia. A screening based on short DNA sequences of the cytochrome c oxidase subunit 1 gene classified the samples into four mitochondrial lineages designated as I-IV. DNA profiles of nuclear genes for DNA polymerase delta (pold) and phosphoenolpyruvate carboxykinase (pepck) showed that lineages II and III can be assigned as two independent species. Common haplotypes of pold and pepck were frequently found in lineages I and IV, suggesting that they constitute a single species. Morphological observations suggested that lineage II is Taenia crocutae, but the other lineages were morphologically inconsistent with known species, suggesting the involvement of two new species. A phylogenetic tree of Taenia spp. was reconstructed by the maximum likelihood method using all protein-coding genes of their mitochondrial genomes. The tree clearly demonstrated that T. crocutae is sister to T. saginata and T. asiatica, whereas T. solium was confirmed to be sister to the brown bear tapeworm, Taenia arctos. The tree also suggested that T. solium and T. arctos are related to two species of Taenia in hyenas, corresponding to lineages I+IV and III. These results may partially support the African origin of human-infecting Taenia spp., but there remains a possibility that host switching of Taenia to hominins was not confined to Africa. Additional taxa from African carnivores are needed for further testing of the "Out of Africa" hypothesis of Taenia in humans."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ijpara.2014.03.013"xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ijpara.2014.03.013"xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Ito A."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Ito A."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Nakao M."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Nakao M."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Okamoto M."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Okamoto M."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Iwaki T."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Iwaki T."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Haukisalmi V."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Haukisalmi V."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Hailemariam Z."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Hailemariam Z."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Lavikainen A."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Lavikainen A."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Menkir S."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Menkir S."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Terefe Y."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/author | "Terefe Y."xsd:string |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24815426 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |