http://purl.uniprot.org/citations/24817020 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24817020 | http://www.w3.org/2000/01/rdf-schema#comment | "The ribosome is responsible for the final step of decoding genetic information into proteins. Therefore, correct assembly of ribosomes is a fundamental task for all living cells. In eukaryotes, the construction of the ribosome which begins in the nucleolus requires coordinated efforts of >350 specialized factors that associate with pre-ribosomal particles at distinct stages to perform specific assembly steps. On their way through the nucleus, diverse energy-consuming enzymes are thought to release assembly factors from maturing pre-ribosomal particles after accomplishing their task(s). Subsequently, recruitment of export factors prepares pre-ribosomal particles for transport through nuclear pore complexes. Pre-ribosomes are exported into the cytoplasm in a functionally inactive state, where they undergo final maturation before initiating translation. Accumulating evidence indicates a tight coupling between nuclear export, cytoplasmic maturation, and final proofreading of the ribosome. In this review, we summarize our current understanding of nuclear export of pre-ribosomal subunits and cytoplasmic maturation steps that render pre-ribosomal subunits translation-competent."xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00412-014-0463-z"xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/author | "Pena C."xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/author | "Panse V.G."xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/author | "Petkowski J.J."xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/author | "Gerhardy S."xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/author | "Menet A.M."xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/name | "Chromosoma"xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/pages | "327-344"xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/title | "Assembly and nuclear export of pre-ribosomal particles in budding yeast."xsd:string |
http://purl.uniprot.org/citations/24817020 | http://purl.uniprot.org/core/volume | "123"xsd:string |
http://purl.uniprot.org/citations/24817020 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24817020 |
http://purl.uniprot.org/citations/24817020 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24817020 |
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http://purl.uniprot.org/uniprot/#_Q06679-mappedCitation-24817020 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24817020 |
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http://purl.uniprot.org/uniprot/#_P38217-mappedCitation-24817020 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24817020 |