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http://purl.uniprot.org/citations/24856897http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24856897http://www.w3.org/2000/01/rdf-schema#comment"

Background aims

Dendritic cell (DC)-based immunotherapy has shown potential to counteract autoimmunity in multiple sclerosis (MS).

Methods

We compared the phenotype and T-cell stimulatory capacity of in vitro generated monocyte-derived DC from MS patients with those from healthy controls.

Results

Except for an increase in the number of C-C chemokine receptor 7-expressing DC from MS patients, no major differences were found between groups in the expression of maturation-associated membrane markers or in the in vitro capacity to stimulate autologous T cells.

Conclusions

Our observations may pave the way for the development of patient-tailored DC-based vaccination strategies to treat MS."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.org/dc/terms/identifier"doi:10.1016/j.jcyt.2014.02.016"xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Cras P."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Berneman Z.N."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Stein B."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Lee W.P."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"D'hooghe M.B."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Goossens H."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Cools N."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Van Tendeloo V.F."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Ponsaerts P."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Willekens B."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Nagels G."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Wouters K."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/author"Nuyts A.H."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/name"Cytotherapy"xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/pages"1024-1030"xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/title"Except for C-C chemokine receptor 7 expression, monocyte-derived dendritic cells from patients with multiple sclerosis are functionally comparable to those of healthy controls."xsd:string
http://purl.uniprot.org/citations/24856897http://purl.uniprot.org/core/volume"16"xsd:string
http://purl.uniprot.org/citations/24856897http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24856897
http://purl.uniprot.org/citations/24856897http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24856897
http://purl.uniprot.org/uniprot/#_A0N0Q0-mappedCitation-24856897http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24856897
http://purl.uniprot.org/uniprot/#_B2R6V6-mappedCitation-24856897http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24856897
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