| http://purl.uniprot.org/citations/24870375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24870375 | http://www.w3.org/2000/01/rdf-schema#comment | "Human leukocyte antigen-G (HLA-G) is known to be implicated in a tumor-driven immune escape mechanism in malignancies. The purpose of this study was to investigate HLA-G polymorphism and expression in breast cancer. HLA-G alleles were determined by direct DNA sequencing procedures from blood samples of 80 breast cancer patients and 80 healthy controls. Soluble HLA-G (sHLA-G) was measured by enzyme-linked immunosorbent assay (ELISA) from serum specimens. HLA-G expression in breast cancer lesions was also analyzed by immunohistochemistry staining. The presence of HLA-G 3' untranslated region (UTR) 14-bp sequence was analyzed and found to be associated with reduced risk of breast cancer susceptibility based on HLA-G expression in tissues (Pā=ā0.0407). Levels of sHLA-G were higher in the breast cancer group (median 117.2 U/mL) compared to the control group (median 10.1 U/mL, P<0.001). The area under the receiver operating characteristic curve (AU-ROC) values of sHLA-G for differentiating breast cancer from normal controls and for detecting metastasis from other stages of breast cancer were 0.89 and 0.79, respectively. HLA-G polymorphism and expression may be involved in breast carcinogenesis and sHLA-G concentrations could be used as a diagnostic marker for detecting breast cancer."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0098284"xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/author | "Kim H.S."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/author | "Park Y."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/author | "Park S."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/author | "Jeong S."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/author | "Park B.W."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/author | "Kwon O.J."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/pages | "e98284"xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/title | "Human leukocyte antigen-G (HLA-G) polymorphism and expression in breast cancer patients."xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://purl.uniprot.org/core/volume | "9"xsd:string |
| http://purl.uniprot.org/citations/24870375 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/24870375 |
| http://purl.uniprot.org/citations/24870375 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/24870375 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9X9-mappedCitation-24870375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24870375 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y0-mappedCitation-24870375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24870375 |
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| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y3-mappedCitation-24870375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24870375 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Y6-mappedCitation-24870375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24870375 |
| http://purl.uniprot.org/uniprot/#_A0A0H4M9Z1-mappedCitation-24870375 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/24870375 |
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