| http://purl.uniprot.org/citations/24876252 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24876252 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/24876252 | http://www.w3.org/2000/01/rdf-schema#comment | "The production of the sperm cells in angiosperms requires coordination of cell division and cell differentiation. In Arabidopsis thaliana, the germline-specific MYB protein DUO1 integrates these processes, but the regulatory hierarchy in which DUO1 functions is unknown. Here, we identify an essential role for two germline-specific DUO1 target genes, DAZ1 and DAZ2, which encode EAR motif-containing C2H2-type zinc finger proteins. We show that DAZ1/DAZ2 are required for germ cell division and for the proper accumulation of mitotic cyclins. Importantly, DAZ1/DAZ2 are sufficient to promote G2-to M-phase transition and germ cell division in the absence of DUO1. DAZ1/DAZ2 are also required for DUO1-dependent cell differentiation and are essential for gamete fusion at fertilization. We demonstrate that the two EAR motifs in DAZ1/DAZ2 mediate their function in the male germline and are required for transcriptional repression and for physical interaction with the corepressor TOPLESS. Our findings uncover an essential module in a regulatory hierarchy that drives mitotic transition in male germ cells and implicates gene repression pathways in sperm cell formation and fertility."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.org/dc/terms/identifier | "doi:10.1105/tpc.114.124743"xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.org/dc/terms/identifier | "doi:10.1105/tpc.114.124743"xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Higashiyama T."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Higashiyama T."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Kumar S."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Kumar S."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Sakamoto W."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Sakamoto W."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Twell D."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Twell D."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Rozwadowski K."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Rozwadowski K."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Borg M."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Borg M."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Esparza-Franco M.A."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Esparza-Franco M.A."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Gherghinoiu M."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Gherghinoiu M."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Hamamura Y."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Hamamura Y."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Kagale S."xsd:string |
| http://purl.uniprot.org/citations/24876252 | http://purl.uniprot.org/core/author | "Kagale S."xsd:string |