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http://purl.uniprot.org/citations/24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24928762http://www.w3.org/2000/01/rdf-schema#comment"Bidirectional promoters are a common feature of many eukaryotic organisms from yeast to humans. RNA Polymerase II that is recruited to this type of promoter can start transcribing in either direction using alternative DNA strands as the template. Such promiscuous transcription can lead to the synthesis of unwanted transcripts that may have negative effects on gene expression. Recent studies have identified transcription termination and gene looping as critical players in the enforcement of promoter directionality. Interestingly, both mechanisms share key components. Here, we focus on recent findings relating to the transcriptional output of bidirectional promoters."xsd:string
http://purl.uniprot.org/citations/24928762http://purl.org/dc/terms/identifier"doi:10.1016/j.tibs.2014.05.001"xsd:string
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/author"Proudfoot N.J."xsd:string
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/author"Grzechnik P."xsd:string
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/author"Tan-Wong S.M."xsd:string
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/name"Trends Biochem Sci"xsd:string
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/pages"319-327"xsd:string
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/title"Terminate and make a loop: regulation of transcriptional directionality."xsd:string
http://purl.uniprot.org/citations/24928762http://purl.uniprot.org/core/volume"39"xsd:string
http://purl.uniprot.org/citations/24928762http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24928762
http://purl.uniprot.org/citations/24928762http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24928762
http://purl.uniprot.org/uniprot/#_P38996-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P39081-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P50105-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P25298-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P25299-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P27999-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P13393-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P16370-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_Q03750-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_Q03761-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P08518-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762
http://purl.uniprot.org/uniprot/#_P23255-mappedCitation-24928762http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/24928762