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http://purl.uniprot.org/citations/24929437http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24929437http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24929437http://www.w3.org/2000/01/rdf-schema#comment"Sexual development in Schizosaccharomyces pombe culminates in meiosis and sporulation. We used ribosome profiling to investigate the translational landscape of this process. We show that the translation efficiency of hundreds of genes is regulated in complex patterns, often correlating with changes in RNA levels. Ribosome-protected fragments show a three-nucleotide periodicity that identifies translated sequences and their reading frame. Using this property, we identified 46 new translated genes and found that 24% of noncoding RNAs are actively translated. We also detected 19 nested antisense genes, in which both DNA strands encode translated mRNAs. Finally, we identified 1,735 translated upstream open reading frames (ORFs) in leader sequences. In S. pombe, in contrast with Saccharomyces cerevisiae, sexual development is not accompanied by large increases in upstream ORF use, thus suggesting that this is an organism-specific adaptation, not a general feature of developmental processes."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.org/dc/terms/identifier"doi:10.1038/nsmb.2843"xsd:string
http://purl.uniprot.org/citations/24929437http://purl.org/dc/terms/identifier"doi:10.1038/nsmb.2843"xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/author"Mata J."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/author"Mata J."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/author"Duncan C.D."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/author"Duncan C.D."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/pages"641-647"xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/pages"641-647"xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/title"The translational landscape of fission-yeast meiosis and sporulation."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/title"The translational landscape of fission-yeast meiosis and sporulation."xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/volume"21"xsd:string
http://purl.uniprot.org/citations/24929437http://purl.uniprot.org/core/volume"21"xsd:string
http://purl.uniprot.org/citations/24929437http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24929437
http://purl.uniprot.org/citations/24929437http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/24929437
http://purl.uniprot.org/citations/24929437http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24929437
http://purl.uniprot.org/citations/24929437http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/24929437
http://purl.uniprot.org/uniprot/Q7Z9I0http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/24929437
http://purl.uniprot.org/uniprot/Q09773http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/24929437