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http://purl.uniprot.org/citations/24958592http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24958592http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/24958592http://www.w3.org/2000/01/rdf-schema#comment"The TCT core promoter element is present in most ribosomal protein (RP) genes in Drosophila and humans. Here we show that TBP (TATA box-binding protein)-related factor TRF2, but not TBP, is required for transcription of the TCT-dependent RP genes. In cells, TCT-dependent transcription, but not TATA-dependent transcription, increases or decreases upon overexpression or depletion of TRF2. In vitro, purified TRF2 activates TCT but not TATA promoters. ChIP-seq (chromatin immunoprecipitation [ChIP] combined with deep sequencing) experiments revealed the preferential localization of TRF2 at TCT versus TATA promoters. Hence, a specialized TRF2-based RNA polymerase II system functions in the synthesis of RPs and complements the RNA polymerase I and III systems."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.org/dc/terms/identifier"doi:10.1101/gad.245662.114"xsd:string
http://purl.uniprot.org/citations/24958592http://purl.org/dc/terms/identifier"doi:10.1101/gad.245662.114"xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Chen K."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Chen K."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Johnston J."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Johnston J."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Wang Y.L."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Wang Y.L."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Kassavetis G.A."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Kassavetis G.A."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Kadonaga J.T."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Kadonaga J.T."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Zeitlinger J."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Zeitlinger J."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Duttke S.H."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/author"Duttke S.H."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/name"Genes Dev."xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/pages"1550-1555"xsd:string
http://purl.uniprot.org/citations/24958592http://purl.uniprot.org/core/pages"1550-1555"xsd:string