http://purl.uniprot.org/citations/24958592 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24958592 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/24958592 | http://www.w3.org/2000/01/rdf-schema#comment | "The TCT core promoter element is present in most ribosomal protein (RP) genes in Drosophila and humans. Here we show that TBP (TATA box-binding protein)-related factor TRF2, but not TBP, is required for transcription of the TCT-dependent RP genes. In cells, TCT-dependent transcription, but not TATA-dependent transcription, increases or decreases upon overexpression or depletion of TRF2. In vitro, purified TRF2 activates TCT but not TATA promoters. ChIP-seq (chromatin immunoprecipitation [ChIP] combined with deep sequencing) experiments revealed the preferential localization of TRF2 at TCT versus TATA promoters. Hence, a specialized TRF2-based RNA polymerase II system functions in the synthesis of RPs and complements the RNA polymerase I and III systems."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.245662.114"xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.245662.114"xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Chen K."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Chen K."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Johnston J."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Johnston J."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Wang Y.L."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Wang Y.L."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Kassavetis G.A."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Kassavetis G.A."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Kadonaga J.T."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Kadonaga J.T."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Zeitlinger J."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Zeitlinger J."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Duttke S.H."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/author | "Duttke S.H."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/pages | "1550-1555"xsd:string |
http://purl.uniprot.org/citations/24958592 | http://purl.uniprot.org/core/pages | "1550-1555"xsd:string |