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http://purl.uniprot.org/citations/2500984http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2500984http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2500984http://www.w3.org/2000/01/rdf-schema#comment"Human liver guanosine triphosphate (GTP) cyclohydrolase I has been purified more than 1,700-fold to what appears to be homogeneity. The active enzyme complex has an estimated molecular weight of 453,000 +/-11,500 by gel filtration chromatography. It consists of a polypeptide of 149,000 +/-4,000 mol wt by SDS-polyacrylamide gel electrophoresis. The activity of the enzyme is heat stable and is inhibited by di- and trivalent cations. The enzyme has an optimum pH of 7.7 in sodium phosphate buffer. It uses GTP as a sole substrate, with a Km of 116 microM."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.org/dc/terms/identifier"doi:10.1016/0300-9084(89)90006-0"xsd:string
http://purl.uniprot.org/citations/2500984http://purl.org/dc/terms/identifier"doi:10.1016/0300-9084(89)90006-0"xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/author"Zhang Y.X."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/author"Zhang Y.X."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/author"Alam A."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/author"Alam A."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/author"Shen R.-S."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/author"Shen R.-S."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/name"Biochimie"xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/name"Biochimie"xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/pages"343-349"xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/pages"343-349"xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/title"Human liver GTP cyclohydrolase I: purification and some properties."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/title"Human liver GTP cyclohydrolase I: purification and some properties."xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/volume"71"xsd:string
http://purl.uniprot.org/citations/2500984http://purl.uniprot.org/core/volume"71"xsd:string
http://purl.uniprot.org/citations/2500984http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2500984
http://purl.uniprot.org/citations/2500984http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2500984
http://purl.uniprot.org/citations/2500984http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2500984
http://purl.uniprot.org/citations/2500984http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2500984