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http://purl.uniprot.org/citations/25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25010547http://www.w3.org/2000/01/rdf-schema#comment"To understand homeostatic regulation in insects, we need to understand the mechanisms by which they respond to external stimuli to maintain the internal milieu. Our previous study showed that Drosophila melanogaster exhibit specific amino acid preferences. Here, we used the D.melanogaster Genetic Reference Panel (DGRP), which is comprised of multiple inbred lines derived from a natural population, to examine how amino acid preference changes depending on the internal nutritional state in different lines. We performed a two-choice preference test and observed genetic variations in the response to amino acid deprivation. For example, a high-responding line showed an enhanced preference for amino acids even after only 1day of deprivation and responded to a fairly low concentration of amino acids. Conversely, a low-responding line showed no increased preference for amino acids after deprivation. We compared the gene expression profiles between selected high- and the low-responding lines and performed SNP analyses. We found several groups of genes putatively involved in altering amino acid preference. These results will contribute to future studies designed to explore how the genetic architecture of an organism evolves to adapt to different nutritional environments."xsd:string
http://purl.uniprot.org/citations/25010547http://purl.org/dc/terms/identifier"doi:10.1016/j.jinsphys.2014.06.019"xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/author"Tanimura T."xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/author"Hara C."xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/author"Scholz C.J."xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/author"Toshima N."xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/name"J Insect Physiol"xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/pages"89-94"xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/title"Genetic variation in food choice behaviour of amino acid-deprived Drosophila."xsd:string
http://purl.uniprot.org/citations/25010547http://purl.uniprot.org/core/volume"69"xsd:string
http://purl.uniprot.org/citations/25010547http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25010547
http://purl.uniprot.org/citations/25010547http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KFJ4-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KFQ4-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KEI9-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KEP9-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KER2-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KET3-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KF62-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KF76-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KF98-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KFA2-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547
http://purl.uniprot.org/uniprot/#_A0A0B4KFD2-mappedCitation-25010547http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/25010547