http://purl.uniprot.org/citations/25034023 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25034023 | http://www.w3.org/2000/01/rdf-schema#comment | "Fibrillins form multifunctional microfibrils in most connective tissues. Deficiencies in fibrillin assembly can result in fibrillinopathies, such as Marfan syndrome. We demonstrate the presence of heparin/heparan sulfate binding sites in fibrillin-2 and -3. Multimerization of all three fibrillins drastically increased the apparent affinity of their interaction with heparin/heparan sulfate. Surprisingly, contrary to other reports heparin/heparan sulfate strongly inhibited homo- and heterotypic N-to-C-terminal fibrillin interactions. These data suggest that heparin/heparan sulfate controls the formation of microfibrils at the bead interaction stage."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2014.06.061"xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/author | "Sabatier L."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/author | "Reinhardt D.P."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/author | "Hubmacher D."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/author | "Djokic J."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/author | "Nelea V."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/author | "Dzafik D."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/pages | "2890-2897"xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/title | "Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly."xsd:string |
http://purl.uniprot.org/citations/25034023 | http://purl.uniprot.org/core/volume | "588"xsd:string |
http://purl.uniprot.org/citations/25034023 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25034023 |
http://purl.uniprot.org/citations/25034023 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25034023 |
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http://purl.uniprot.org/uniprot/P35555 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25034023 |
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