http://purl.uniprot.org/citations/25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25062414 | http://www.w3.org/2000/01/rdf-schema#comment | "Behçet's disease (BD) is a multisystemic inflammatory disease believed to be triggered by microbial or environmental factors on a genetic platform. Clinically, it may have an impact on many body systems, including the mucocutaneous, ocular, articular, vascular, and neurological systems. In this study, we aimed to determine the HLA-B51 subtypes and their correlations with the clinical findings of BD. Fifty-one patients with BD and 44 gender- and age-matched healthy subjects were included in this study. The HLA-B51 subtypes of all participants were determined, and the correlations of the clinical manifestations of the disease with the HLA-B51 subtypes were analyzed. HLA-B51 positivity was found to be significantly higher in the patient group (P < 0.001, RR = 15.20), which had significantly more frequent HLA-B5101, HLA-B5102(01), HLA-B5109, and HLA-B5122 subtypes than the healthy subjects (all P < 0.05). Furthermore, considering the correlation between the genetic makeup and clinical findings, the HLA-B5109 subtype was found to be less frequent in patients with papulopustular skin lesions (P = 0.042). The frequency of HLA-B5103 was significantly higher in patients with central nervous system involvement (P = 0.015). There may be a relationship between HLA-B5102(01), HLA-B5109, and HLA-B5122 in addition to HLA-B51 and HLA-B5101(01) in Turkish patients with BD. The HLA-B5109 subtype can be protective against papulopustular lesion development; however, the HLA-B5103 subtype may pose a risk for neuro-Behçet development in BD."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.org/dc/terms/identifier | "doi:10.4238/2014.july.2.8"xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/author | "Emre S."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/author | "Metin A."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/author | "Arman A."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/author | "Ceylan G.G."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/author | "Erten S."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/author | "Akoglu G."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/author | "Demirseren D.D."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/name | "Genet Mol Res"xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/pages | "4788-4796"xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/title | "HLA-B51 subtypes in Turkish patients with Behcet's disease and their correlation with clinical manifestations."xsd:string |
http://purl.uniprot.org/citations/25062414 | http://purl.uniprot.org/core/volume | "13"xsd:string |
http://purl.uniprot.org/citations/25062414 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25062414 |
http://purl.uniprot.org/citations/25062414 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25062414 |
http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |
http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |
http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |
http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |
http://purl.uniprot.org/uniprot/#_A0A068B107-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |
http://purl.uniprot.org/uniprot/#_A0A068B112-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |
http://purl.uniprot.org/uniprot/#_A0A068B116-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |
http://purl.uniprot.org/uniprot/#_A0A068B2J5-mappedCitation-25062414 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25062414 |