| http://purl.uniprot.org/citations/25088770 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25088770 | http://www.w3.org/2000/01/rdf-schema#comment | "Group 2 innate lymphoid cells (ILC2s) release interleukin-13 (IL-13) during protective immunity to helminth infection and detrimentally during allergy and asthma. Using two mouse models to deplete ILC2s in vivo, we demonstrate that T helper 2 (Th2) cell responses are impaired in the absence of ILC2s. We show that MHCII-expressing ILC2s interact with antigen-specific T cells to instigate a dialog in which IL-2 production from T cells promotes ILC2 proliferation and IL-13 production. Deletion of MHCII renders IL-13-expressing ILC2s incapable of efficiently inducing Nippostrongylus brasiliensis expulsion. Thus, during transition to adaptive T cell-mediated immunity, the ILC2 and T cell crosstalk contributes to their mutual maintenance, expansion and cytokine production. This interaction appears to augment dendritic-cell-induced T cell activation and identifies a previously unappreciated pathway in the regulation of type-2 immunity."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.immuni.2014.06.016"xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Brewer J.M."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Walker J.A."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Wong S.H."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "McKenzie A.N."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Ogg G.S."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Fallon P.G."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Hams E."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Salimi M."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Hwang Y.Y."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Scanlon S.T."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Barlow J.L."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Oliphant C.J."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/author | "Englezakis A."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/pages | "283-295"xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/title | "MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion."xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://purl.uniprot.org/core/volume | "41"xsd:string |
| http://purl.uniprot.org/citations/25088770 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25088770 |
| http://purl.uniprot.org/citations/25088770 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25088770 |
| http://purl.uniprot.org/uniprot/#_A0A2I3BRC2-mappedCitation-25088770 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25088770 |
| http://purl.uniprot.org/uniprot/#_B6DXE3-mappedCitation-25088770 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25088770 |