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http://purl.uniprot.org/citations/25096880http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25096880http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25096880http://www.w3.org/2000/01/rdf-schema#comment"Uncultured and therefore uncharacterized Bacteroidetes lineages are ubiquitous in many natural ecosystems which specialize in lignocellulose degradation. However, their metabolic contribution remains mysterious, as well-studied cultured Bacteroidetes have been shown to degrade only soluble polysaccharides within the human distal gut and herbivore rumen. We have interrogated a reconstructed genome from an uncultured Bacteroidetes phylotype that dominates a switchgrass-associated community within the cow rumen. Importantly, this characterization effort has revealed the first preliminary evidence for polysaccharide utilization locus (PUL)-catalyzed conversion of cellulose. Based on these findings, we propose a further expansion of the PUL paradigm and the saccharolytic capacity of rumen Bacteroidetes species to include cellulose, the most abundant terrestrial polysaccharide on Earth. Moreover, the perspective of a cellulolytic PUL lays the foundation for PULs to be considered an alternative mechanism for cellulose degradation, next to cellulosomes and free-enzyme systems."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.org/dc/terms/identifier"doi:10.1128/mBio.01401-14"xsd:string
http://purl.uniprot.org/citations/25096880http://purl.org/dc/terms/identifier"doi:10.1128/mbio.01401-14"xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Eijsink V.G."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Eijsink V.G."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Mravec J."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Mravec J."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Willats W.G."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Willats W.G."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Pope P.B."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Pope P.B."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Mackenzie A.K."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Mackenzie A.K."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Naas A.E."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Naas A.E."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Schuckel J."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/author"Schuckel J."xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/name"MBio"xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/name"mBio"xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/pages"e01401-e01414"xsd:string
http://purl.uniprot.org/citations/25096880http://purl.uniprot.org/core/pages"e01401-14"xsd:string