| http://purl.uniprot.org/citations/25154419 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25154419 | http://www.w3.org/2000/01/rdf-schema#comment | "What has been will be again, what has been done will be done again; there is nothing new under the sun. -Ecclesiastes 1:9 (New International Version) Posttranscriptional regulation of gene expression has an important role in defining the phenotypic characteristics of an organism. Well-defined steps in mRNA metabolism that occur in the nucleus-capping, splicing, and polyadenylation-are mechanistically linked to the process of transcription. Recent evidence suggests another link between RNA polymerase II (Pol II) and a posttranscriptional process that occurs in the cytoplasm-mRNA decay. This conclusion appears to represent a conundrum. How could mRNA synthesis in the nucleus and mRNA decay in the cytoplasm be mechanistically linked? After a brief overview of mRNA processing, we will review the recent evidence for transcription-coupled mRNA decay and the possible involvement of Snf1, the Saccharomyces cerevisiae ortholog of AMP-activated protein kinase, in this process."xsd:string |
| http://purl.uniprot.org/citations/25154419 | http://purl.org/dc/terms/identifier | "doi:10.1128/mcb.00535-14"xsd:string |
| http://purl.uniprot.org/citations/25154419 | http://purl.uniprot.org/core/author | "Young E.T."xsd:string |
| http://purl.uniprot.org/citations/25154419 | http://purl.uniprot.org/core/author | "Braun K.A."xsd:string |
| http://purl.uniprot.org/citations/25154419 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/25154419 | http://purl.uniprot.org/core/name | "Mol Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/25154419 | http://purl.uniprot.org/core/pages | "4078-4087"xsd:string |
| http://purl.uniprot.org/citations/25154419 | http://purl.uniprot.org/core/title | "Coupling mRNA synthesis and decay."xsd:string |
| http://purl.uniprot.org/citations/25154419 | http://purl.uniprot.org/core/volume | "34"xsd:string |
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