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http://purl.uniprot.org/citations/25190797http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25190797http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25190797http://www.w3.org/2000/01/rdf-schema#comment"Coupled translocation of messenger RNA and transfer RNA (tRNA) through the ribosome, a process catalyzed by elongation factor EF-G, is a crucial step in protein synthesis. The crystal structure of a bacterial translocation complex describes the binding states of two tRNAs trapped in mid-translocation. The deacylated P-site tRNA has moved into a partly translocated pe/E chimeric hybrid state. The anticodon stem-loop of the A-site tRNA is captured in transition toward the 30S P site, while its 3' acceptor end contacts both the A and P loops of the 50S subunit, forming an ap/ap chimeric hybrid state. The structure shows how features of ribosomal RNA rearrange to hand off the A-site tRNA to the P site, revealing an active role for ribosomal RNA in the translocation process."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.org/dc/terms/identifier"doi:10.1126/science.1255030"xsd:string
http://purl.uniprot.org/citations/25190797http://purl.org/dc/terms/identifier"doi:10.1126/science.1255030"xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Zhou J."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Zhou J."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Noller H.F."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Noller H.F."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Lancaster L."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Lancaster L."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Donohue J.P."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/author"Donohue J.P."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/pages"1188-1191"xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/pages"1188-1191"xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/title"How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/title"How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation."xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/volume"345"xsd:string
http://purl.uniprot.org/citations/25190797http://purl.uniprot.org/core/volume"345"xsd:string
http://purl.uniprot.org/citations/25190797http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25190797
http://purl.uniprot.org/citations/25190797http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/25190797