| http://purl.uniprot.org/citations/25218344 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/25218344 | http://www.w3.org/2000/01/rdf-schema#comment | "miRNAs have extensive functions in differentiation, metabolism, programmed cell death, and tumor metastasis by post-transcriptional regulation. Vasculogenic mimicry is an important pathway in tumor metastasis. Many factors can regulate vasculogenic mimicry, including miRNAs. In previous studies, miR-124 was found to repress proliferation and metastasis in different types of cancers, but whether it functions in cervical cancer remained unknown. Here, we demonstrate that miR-124 can repress vasculogenic mimicry, migration and invasion in HeLa and C33A cells in vitro. Furthermore, we reveal that the effect of miR-124 on vasculogenic mimicry, migration and invasion results from its interaction with AmotL1. MiR-124 regulates AmotL1 negatively by targeting its 3'untranslated region (3'UTR). We found that miR-124 can repress the EMT process. Together, these results improve our understanding of the function of miR-124 in tumor metastasis and will help to provide new potential target sites for cervical cancer treatment."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.canlet.2014.09.005"xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Liu M."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Tang H."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Tian W."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Li Q.Q."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Li Y.N."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/author | "Wan H.Y."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/name | "Cancer Lett"xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/pages | "148-158"xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/title | "MiR-124 represses vasculogenic mimicry and cell motility by targeting amotL1 in cervical cancer cells."xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://purl.uniprot.org/core/volume | "355"xsd:string |
| http://purl.uniprot.org/citations/25218344 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/25218344 |
| http://purl.uniprot.org/citations/25218344 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/25218344 |
| http://purl.uniprot.org/uniprot/#_Q8IY63-mappedCitation-25218344 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25218344 |
| http://purl.uniprot.org/uniprot/#_Q8N209-mappedCitation-25218344 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/25218344 |
| http://purl.uniprot.org/uniprot/Q8N209 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25218344 |
| http://purl.uniprot.org/uniprot/Q8IY63 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/25218344 |