http://purl.uniprot.org/citations/25242865 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25242865 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/25242865 | http://www.w3.org/2000/01/rdf-schema#comment | "Secretoglobin (SCGB) 3A2, a cytokine-like secretory protein of small molecular weight, which may play a role in lung inflammation, is predominantly expressed in airway epithelial cells. In order to understand the physiological role of SCGB3A2, Scgb3a2(-/-) mice were generated and characterized. Scgb3a2(-/-) mice did not exhibit any overt phenotypes. In ovalbumin-(OVA-) induced airway allergy inflammation model, Scgb3a2(-/-) mice in mixed background showed a decreased OVA-induced airway inflammation, while six times C57BL/6NCr backcrossed congenic Scgb3a2(-/-) mice showed a slight exacerbation of OVA-induced airway inflammation as compared to wild-type littermates. These results indicate that the loss of SCGB3A2 function was influenced by a modifier gene(s) in mixed genetic background and suggest that SCGB3A2 has anti-inflammatory property. The results further suggest the possible use of recombinant human SCGB3A2 as an anti-inflammatory agent."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.org/dc/terms/identifier | "doi:10.1155/2014/216465"xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.org/dc/terms/identifier | "doi:10.1155/2014/216465"xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Cai Y."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Cai Y."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Kimura S."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Kimura S."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Ward J.M."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Ward J.M."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Matsubara T."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Matsubara T."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Yoneda M."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Yoneda M."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Kido T."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/author | "Kido T."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/date | "2014"xsd:gYear |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/name | "Mediators Inflamm."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/name | "Mediators Inflamm."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/pages | "216465"xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/pages | "216465"xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/title | "Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation."xsd:string |
http://purl.uniprot.org/citations/25242865 | http://purl.uniprot.org/core/title | "Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation."xsd:string |