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http://purl.uniprot.org/citations/25242865http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25242865http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/25242865http://www.w3.org/2000/01/rdf-schema#comment"Secretoglobin (SCGB) 3A2, a cytokine-like secretory protein of small molecular weight, which may play a role in lung inflammation, is predominantly expressed in airway epithelial cells. In order to understand the physiological role of SCGB3A2, Scgb3a2(-/-) mice were generated and characterized. Scgb3a2(-/-) mice did not exhibit any overt phenotypes. In ovalbumin-(OVA-) induced airway allergy inflammation model, Scgb3a2(-/-) mice in mixed background showed a decreased OVA-induced airway inflammation, while six times C57BL/6NCr backcrossed congenic Scgb3a2(-/-) mice showed a slight exacerbation of OVA-induced airway inflammation as compared to wild-type littermates. These results indicate that the loss of SCGB3A2 function was influenced by a modifier gene(s) in mixed genetic background and suggest that SCGB3A2 has anti-inflammatory property. The results further suggest the possible use of recombinant human SCGB3A2 as an anti-inflammatory agent."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.org/dc/terms/identifier"doi:10.1155/2014/216465"xsd:string
http://purl.uniprot.org/citations/25242865http://purl.org/dc/terms/identifier"doi:10.1155/2014/216465"xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Cai Y."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Cai Y."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Kimura S."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Kimura S."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Ward J.M."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Ward J.M."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Matsubara T."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Matsubara T."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Yoneda M."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Yoneda M."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Kido T."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/author"Kido T."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/date"2014"xsd:gYear
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/name"Mediators Inflamm."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/name"Mediators Inflamm."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/pages"216465"xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/pages"216465"xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/title"Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation."xsd:string
http://purl.uniprot.org/citations/25242865http://purl.uniprot.org/core/title"Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation."xsd:string